affliction

nouns

a state of great suffering and distress due to adversity
is derived from
is derived from
is a type of (narrower)
a state of misfortune or affliction
"debt-ridden farmers struggling with adversity"; "a life of hardship"
a condition of suffering or distress due to ill health
is a type of (narrower)
a state in which you are unable to function normally and without pain
a cause of great suffering and distress
is derived from
is a type of (narrower)
an event causing distress or pain
"what is the trouble?"; "heart trouble"