verbs
wear out completely
"This kind of work exhausts me"; "I'm beat"; "He was all washed up after the exam"
use up (resources or materials)
"this car consumes a lot of gas"; "We exhausted our savings"; "They run through 20 bottles of wine a week"
deplete
"exhaust one's savings"; "We quickly played out our strength"
use up the whole supply of
"We have exhausted the food supplies"
is a type of (narrower)
make void or empty of contents
"Empty the box"; "The alarm emptied the building"
eliminate (a substance)
"combustion products are exhausted in the engine"; "the plant releases a gas"