exhausted

adjectives

drained of energy or effectiveness; extremely tired; completely exhausted
"the day's shopping left her exhausted"; "he went to bed dog-tired"; "was fagged and sweaty"; "the trembling of his played out limbs"; "felt completely washed-out"; "only worn-out horses and cattle"; "you look worn out"
depleted of energy, force, or strength
"impossible to grow tobacco on the exhausted soil"; "the exhausted food sources"; "exhausted oil wells"
antonym
drained physically
"the day's events left her completely exhausted--her strength drained"
is similar to
emptied or exhausted of (as by drawing off e.g. water or other liquid)
"a drained marsh"; "a drained tank"; "a drained and apathetic old man...not caring any longer about anything"