catastrophe

nouns

an event resulting in great loss and misfortune
"the whole city was affected by the irremediable calamity"; "the earthquake was a disaster"
calamity, cataclysm, catastrophe, disaster, tragedy
a state of extreme (usually irremediable) ruin and misfortune
"lack of funds has resulted in a catastrophe for our school system"; "his policies were a disaster"
catastrophe, disaster
a sudden violent change in the earth's surface
cataclysm, catastrophe