disaster

nouns

a state of extreme (usually irremediable) ruin and misfortune
"lack of funds has resulted in a catastrophe for our school system"; "his policies were a disaster"
an event resulting in great loss and misfortune
"the whole city was affected by the irremediable calamity"; "the earthquake was a disaster"
is derived from
an act that has disastrous consequences
is a type of (narrower)
the termination of something by causing so much damage to it that it cannot be repaired or no longer exists