pain

nouns

a symptom of some physical hurt or disorder
"the patient developed severe pain and distension"
hurting, pain
emotional distress; a fundamental feeling that people try to avoid
"the pain of loneliness"
pain, painfulness
antonym
pleasure
a somatic sensation of acute discomfort
"as the intensity increased the sensation changed from tickle to pain"
pain, pain sensation, painful sensation
a bothersome annoying person
"that kid is a terrible pain"
nuisance, pain, pain in the neck
something or someone that causes trouble; a source of unhappiness
"washing dishes was a nuisance before we got a dish washer"; "a bit of a bother"; "he's not a friend, he's an infliction"
annoyance, bother, botheration, infliction, pain, pain in the ass, pain in the neck

verbs

cause bodily suffering to and make sick or indisposed
ail, pain, trouble
cause emotional anguish or make miserable
"It pains me to see my children not being taught well in school"
anguish, hurt, pain